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Author: avallecam

instructors/04-practical-tutors.qmd

@@ -421,7 +421,7 @@ Interpretation Helpers:
 
 + School closure starting on day 200 for a duration of 250 days can delay the peak of infectious across age groups by 240 days aprox., and reduce the total number of new infections in the whole population by 20,000 aprox.
 + Mask mandate starting on day 200 for a duration of 250 days can delay the peak of infectious across age groups by 40 days aprox., and reduce the total number of new infections in the whole population by 50,000 aprox.
-+ Vaccinations starting on day 200 for a duration of 250 days can delay the peak of infectious across age groups by 4 days aprox., and reduce the total number of new infections in the whole population by 40,000 aprox. 
++ Vaccinations starting on day 200 for a duration of 250 days will not delay the peak of infectious across age groups, but reduce the total number of new infections in the whole population by 40,000 aprox. 
     + Note that the effectiveness of vaccination can depend on various factors, including **vaccine efficacy** and **timing relative to the outbreak**.
 
 ### Additional challenges
@@ -437,7 +437,7 @@ Try modifying the intervention start time from day 200 to day 100, or changing t
 
 ## Activity 3: Combine Multiple Interventions
 
-Compare the baseline scenario with a simulation that includes two interventions applied simultaneously. Use the intervention parameters described in the previous activity.
+Compare the baseline scenario with a simulation that includes two overlapping or sequential interventions. Use the intervention parameters described in the previous activity.
 
 **Steps:**  
 
@@ -547,16 +547,53 @@ Write your answers to the questions above:
 
 #### Outputs
 
-| Combine interventions | Compare interventions |
-|---|---|
-| ![image](https://hackmd.io/_uploads/rk9cqK_CJe.png) | ![image](https://hackmd.io/_uploads/BJro5KuC1e.png) |
+
+| room 1 | room 2 | room 3 |
+| --- | --- | --- |
+| ![image](https://hackmd.io/_uploads/Bk_gXjQwex.png) | ![image](https://hackmd.io/_uploads/rylgZiXPeg.png) | ![image](https://hackmd.io/_uploads/S1KyEsXwgg.png) |
+
+room 1
+
+```
+epidemics::epidemic_peak(simulate_twointerventions)
+#>    demography_group compartment  time    value
+#> 1:           [0,20)  infectious   201 7078.228
+#> 2:          [20,40)  infectious   261 7677.865
+#> 3:              40+  infectious   260 5131.311
+```
+
+room 2
+
+```
+epidemics::epidemic_peak(simulate_twointerventions)
+#>    demography_group compartment  time    value
+#> 1:           [0,20)  infectious   648 253705.5
+#> 2:          [20,40)  infectious   647 170917.0
+#> 3:              40+  infectious   642 100149.4
+```
+
+room 3
+
+```
+epidemics::epidemic_peak(simulate_twointerventions)
+#>    demography_group compartment time    value
+#> 1:           [0,20)  infectious  324 29117.39
+#> 2:          [20,40)  infectious  324 20627.33
+#> 3:              40+  infectious  322 13569.35
+```
 
 #### Interpretation
 
 Interpretation Helpers:
 
-- The combination of school closure and mask mandate can delay the epidemic peak, but will not reduce it size.
-- Vaccination can sustain a reduced epidemic peak compared with mask mandate alone.
++ Overlapping School closure and Vaccinations can have an earlier peak of infectious across age groups by 100 days aprox., and reduce the total number of new infections in the whole population by 75,000 aprox. 
++ Overlapping Mask mandate and School closure can delay the peak of infectious across age groups by 300 days aprox., and reduce the total number of new infections in the whole population by 10,000 aprox. 
++ Overlapping Mask mandate and Vaccination will not change the time of peak of infectious across age groups, but reduce the total number of new infections in the whole population by 70,000 aprox. 
+
+### Additional challenge
+
+1. **What sequence of interventions would you propose to delay the peak and reduce the impact of the epidemic?**
+Experiment by independently adjusting the start time and duration of each intervention. Implement them either sequentially or with overlapping periods, and observe their effects on the epidemic dynamics in Zimbabwe. This can support a response plan that allows time for risk assessment and efficient resource allocation.
 
 ## Code