diff --git a/Cargo.lock b/Cargo.lock
index c3f17c5..98707f4 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -2,15 +2,6 @@
 # It is not intended for manual editing.
 version = 4
 
-[[package]]
-name = "addr2line"
-version = "0.24.2"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "dfbe277e56a376000877090da837660b4427aad530e3028d44e0bffe4f89a1c1"
-dependencies = [
- "gimli",
-]
-
 [[package]]
 name = "adler2"
 version = "2.0.1"
@@ -453,21 +444,6 @@ dependencies = [
  "tokio",
 ]
 
-[[package]]
-name = "backtrace"
-version = "0.3.75"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "6806a6321ec58106fea15becdad98371e28d92ccbc7c8f1b3b6dd724fe8f1002"
-dependencies = [
- "addr2line",
- "cfg-if",
- "libc",
- "miniz_oxide",
- "object",
- "rustc-demangle",
- "windows-targets 0.52.6",
-]
-
 [[package]]
 name = "base64"
 version = "0.22.1"
@@ -2071,12 +2047,6 @@ dependencies = [
  "wasm-bindgen",
 ]
 
-[[package]]
-name = "gimli"
-version = "0.31.1"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "07e28edb80900c19c28f1072f2e8aeca7fa06b23cd4169cefe1af5aa3260783f"
-
 [[package]]
 name = "glob"
 version = "0.3.3"
@@ -2485,17 +2455,6 @@ version = "3.0.4"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "8bb03732005da905c88227371639bf1ad885cc712789c011c31c5fb3ab3ccf02"
 
-[[package]]
-name = "io-uring"
-version = "0.7.10"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "046fa2d4d00aea763528b4950358d0ead425372445dc8ff86312b3c69ff7727b"
-dependencies = [
- "bitflags",
- "cfg-if",
- "libc",
-]
-
 [[package]]
 name = "ipnet"
 version = "2.11.0"
@@ -3518,15 +3477,6 @@ version = "0.4.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "830b246a0e5f20af87141b25c173cd1b609bd7779a4617d6ec582abaf90870f3"
 
-[[package]]
-name = "object"
-version = "0.36.7"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "62948e14d923ea95ea2c7c86c71013138b66525b86bdc08d2dcc262bdb497b87"
-dependencies = [
- "memchr",
-]
-
 [[package]]
 name = "object_store"
 version = "0.12.3"
@@ -4258,12 +4208,6 @@ dependencies = [
  "ordered-multimap",
 ]
 
-[[package]]
-name = "rustc-demangle"
-version = "0.1.26"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "56f7d92ca342cea22a06f2121d944b4fd82af56988c270852495420f961d4ace"
-
 [[package]]
 name = "rustc-hash"
 version = "2.1.1"
@@ -4876,29 +4820,26 @@ checksum = "1f3ccbac311fea05f86f61904b462b55fb3df8837a366dfc601a0161d0532f20"
 
 [[package]]
 name = "tokio"
-version = "1.47.1"
+version = "1.48.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "89e49afdadebb872d3145a5638b59eb0691ea23e46ca484037cfab3b76b95038"
+checksum = "ff360e02eab121e0bc37a2d3b4d4dc622e6eda3a8e5253d5435ecf5bd4c68408"
 dependencies = [
- "backtrace",
  "bytes",
- "io-uring",
  "libc",
  "mio",
  "parking_lot",
  "pin-project-lite",
  "signal-hook-registry",
- "slab",
  "socket2",
  "tokio-macros",
- "windows-sys 0.59.0",
+ "windows-sys 0.61.2",
 ]
 
 [[package]]
 name = "tokio-macros"
-version = "2.5.0"
+version = "2.6.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "6e06d43f1345a3bcd39f6a56dbb7dcab2ba47e68e8ac134855e7e2bdbaf8cab8"
+checksum = "af407857209536a95c8e56f8231ef2c2e2aff839b22e07a1ffcbc617e9db9fa5"
 dependencies = [
  "proc-macro2",
  "quote",
@@ -4927,9 +4868,9 @@ dependencies = [
 
 [[package]]
 name = "tokio-util"
-version = "0.7.16"
+version = "0.7.17"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "14307c986784f72ef81c89db7d9e28d6ac26d16213b109ea501696195e6e3ce5"
+checksum = "2efa149fe76073d6e8fd97ef4f4eca7b67f599660115591483572e406e165594"
 dependencies = [
  "bytes",
  "futures-core",
diff --git a/Cargo.toml b/Cargo.toml
index eedb0c6..5f46032 100644
--- a/Cargo.toml
+++ b/Cargo.toml
@@ -27,8 +27,8 @@ noodles-bgzf = { version = "0.36.0",features = ["libdeflate"] }
 noodles-cram  = { git = "https://github.com/biodatageeks/noodles.git",rev = "d6f205e9bb5369762236724fb54d24c5e1d9b79a", features = ["async"] }
 noodles-sam = { git = "https://github.com/biodatageeks/noodles.git",rev = "d6f205e9bb5369762236724fb54d24c5e1d9b79a" }
 noodles-fasta = { git = "https://github.com/biodatageeks/noodles.git",rev = "d6f205e9bb5369762236724fb54d24c5e1d9b79a", features = ["async"] }
-tokio = { version = "1.43.0", features = ["rt-multi-thread", "rt", "macros"] }
-tokio-util = {  version="0.7.13", features = ["io-util", "compat"] }
+tokio = { version = "1.48.0", features = ["rt-multi-thread", "rt", "macros"] }
+tokio-util = {  version="0.7.17", features = ["io-util", "compat"] }
 bytes = "1.10.0"
 futures = "0.3.31"
 async-stream = "0.3.6"
diff --git a/benchmarks/common/Cargo.toml b/benchmarks/common/Cargo.toml
index ff6a60f..abe1285 100644
--- a/benchmarks/common/Cargo.toml
+++ b/benchmarks/common/Cargo.toml
@@ -13,7 +13,7 @@ serde = { version = "1.0", features = ["derive"] }
 serde_json = "1.0"
 reqwest = { version = "0.12", features = ["blocking", "stream"] }
 sha2 = "0.10"
-tokio = { version = "1.43", features = ["full"] }
+tokio = { version = "1.48", features = ["full"] }
 chrono = { version = "0.4", features = ["serde"] }
 sysinfo = "0.32"
 anyhow = "1.0"
diff --git a/benchmarks/runner/Cargo.toml b/benchmarks/runner/Cargo.toml
index 834700d..8d62328 100644
--- a/benchmarks/runner/Cargo.toml
+++ b/benchmarks/runner/Cargo.toml
@@ -32,7 +32,7 @@ serde_yaml = "0.9"
 serde_json = "1.0"
 
 # Async runtime and error handling
-tokio = { version = "1.43", features = ["full"] }
+tokio = { version = "1.48", features = ["full"] }
 anyhow = "1.0"
 
 # Logging