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# RapidCharacterisationProtocols
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Collection of protocols for rapid characterisation of ion channels, in both plain text format and csv format.
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Collection of protocols for rapid characterisation of ion channels, in both plain text `.txt` and comma-separated-value `.csv` formats.
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## Sinusoidal voltage clamp for hERG/IKr measurements
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The first protocol is `sinewave-ramp` which is a slightly-updated version of the sinusoidal voltage clamp we first published in 2018 (which has a dedicated [Github repository](http://www.github.com/mirams/sine-wave)). The update here is a ramp during the initial 'leak step' rather than a fixed potential.
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# Format/Units
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Each file has two columns, the first one is time (in [second]) and the second column is voltage (in [mV]).
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Each file has two columns, the first one is time (in [seconds]) and the second column is voltage (in [milliVolts]).
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# Acknowledging this work
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If you publish any work based on the contents of this repository please cite:
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Beattie, K. A., Hill, A. P., Bardenet, R., Cui, Y., Vandenberg, J. I., Gavaghan, D. J., de Boer, T. P. & Mirams, G. R. [Sinusoidal voltage protocols for rapid characterisation of ion channel kinetics](https://doi.org/10.1113/JP275733). J. Physiol. 596, 1813–1828 (2018).

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